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What's the research question we'll be answering?

The research question we're asking with the Megathon dataset is whether stalls occur more in the brain of mice that have high blood pressure, and whether that stalling can be reversed. If that turns out to be true, it would suggest that high blood pressure may cause or aggravate capillary stalling, and that this could be one mechanism that links hypertension to an increased risk and severity of Alzheimer's disease. Also, if true, this could suggest that individuals with high blood pressure may be candidates to for a preventive future treatment to reduce capillary stalling.