Science - Human Computation Institute Blogs (Page 2)

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A collection of 43 posts

The Long Term dataset

Next in Stall Catchers [https://stallcatchers.com] we are working on the "Long Term" dataset. With the "Long Term" dataset we are seeking to understand how late into disease development an increase in brain blood flow, due to a decrease in capillary stalling, still leads to

The "Hypertension" dataset is complete! Here's the full report...

The "Hypertension" dataset is complete! Here's the full report...

Fanfares 🎺 Another datase is complete in Stall Catchers [https://stallcatchers.com]! This time we are looking to find out if high blood pressure affects the rate of stalls in Alzheimer's mice. See the full dataset report below! P.S. the official research result will come later, after the

Early peek at the #Megathon research result 📈 📊

Early peek at the #Megathon research result 📈 📊

As you know, as of Monday this week, we completed the first pass [https://blog.eyesonalz.com/megathon-results] of the Megathon dataset analysis, which allows us to take a peek at your answers and, as promised, provide a preliminary research result! However, let me start with the reminder that all

🎥 Lecture: the role of reduced blood flow in Alzheimer's & the Stall Catchers game

Last Friday, Pietro gave a talk at Cornell University alongside our biomedical collaborators Nozomi & Chris. The lecture covers the aspects of the science behind Stall Catchers, i.e. the role of stalls and reduced blood flow in the brain in Alzheimer's, as well as the inception and

The time of NOX is over. The time of Tau has come. (Wait what?! 😅)

The time of NOX is over. The time of Tau has come. (Wait what?! 😅)

Here comes the long overdue update on the research YOU are helping to achieve on Stall Catchers [https://stallcatchers.com/virtualMicroscope] ! In short: we have just finished the "NOX" dataset -- the very first dataset looking into molecular mechanisms behind stall formation. Stall Catchers [https://stallcatchers.com/] is

Article in "Nature Neuroscience" describes the role of stalls in Alzheimer's for the first time -- translation to human here 👇

Article in "Nature Neuroscience" describes the role of stalls in Alzheimer's for the first time -- translation to human here 👇

The basis for everything we do in Stall Catchers [https://stallcatchers.com] was published in the article "Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models" by our collaborators at Cornell University in Nature Neuroscience today. → Read the

What does it take to become a vessel expert in Stall Catchers? Interview with our rock star Torie! ♥

The Humans of Stall Catchers

What does it take to become a vessel expert in Stall Catchers? Interview with our rock star Torie! ♥

Why can't Cornell University researchers do their work Alzheimer's research work effectively without the help of citizen scientists? What does it take to become an expert in recognizing stalls? Interview with Victorine (Torie) Muse -- the rock star of Stall Catchers and a former Master'

Stall Catchers doesn't just speed up research -- it enables it! Interview with Prof. Nozomi Nishimura

Stall Catchers [https://stallcatchers.com/] doesn't just speed up the research at Cornell University - it enables researchers to ask questions that they haven't been able to ask before. Wonderfully explained in this interview with our collaborator, Prof. Nozomi Nishimura: Help us do new kinds of

The Science Behind EyesOnALZ

The Science Behind EyesOnALZ

In the early days of our existence (I mean EyesOnALZ, not the Universe 😇) we published a blog series about the project on the SciStarter/DiscoverMag/PLOS Blogs networks. We're sharing the selected content here! The following post, orig. titled "The Science Behind WeCureALZ * : A Participatory Research Project

Where does the research behind Stall Catchers happen? Interview with Prof. Chris Schaffer

In Stall Catchers [https://stallcatchers.com/], you - our volunteer catchers - are analyzing movies from a mouse brain, looking for stalled blood vessels. But where do these "movies" come from? Who are our biomedical collaborators doing this research? Why are they so interested, and how does this

Science of Stall Catchers: Our new Magic Number 🔮✨

Science of Stall Catchers: Our new Magic Number 🔮✨

Ever wonder how we get reliable crowd answers in Stall Catchers [https://stallcatchers.com/]? Well, there's a special kind of magic for that! Our goal with Stall Catchers [https://stallcatchers.com/] is to use crowd power to speed up the analysis of Alzheimer's disease research data.

Science of Stall Catchers: the High Fat Diet dataset

Science of Stall Catchers: the High Fat Diet dataset

Right now in Stall Catchers [https://stallcatchers.com/main], our catchers are analyzing a dataset concerned with the role of a high fat diet in the formation of stalls. What does that mean? What research questions are we trying to answer? How are catchers helping us answer them? All explained

We're looking for an "effective treatment" for Alzheimer's. What does that mean?

We're looking for an "effective treatment" for Alzheimer's. What does that mean?

What do we mean by "Effective Treatment"? I was talking with EyesOnALZ colleague Lisa Gusman today, who has created some amazing educational videos for Stall Catchers [http://stallcatchers.com], like this one: She aptly pointed out that when we talk about goals and expectations for Stall Catchers [http:

Science of Stall Catchers: discovery-based or hypothesis-driven?

Science of Stall Catchers: discovery-based or hypothesis-driven?

We received an interesting question from one of our catchers, tova, about whether Stall Catchers [http://stallcatchers.com] is based on discovery-based or hypothesis-driven science. I thought it might be interesting for everyone to know that, so here is Pietro's answer to that below! It's primarily

New dataset in Stall Catchers - high fat diet

New dataset in Stall Catchers - high fat diet

Just in time for the catchathon [http://blog.eyesonalz.com/whats-a-catchathon/], our biomedical collaborators - the Schaffer-Nishimura Lab, prepared a fresh dataset for us to analyze in Stall Catchers [https://stallcatchers.com/main]! The new dataset is focused on the effects of a high fat diet on stalls in the

How does playing Stall Catchers help fight Alzheimer's?

How does playing Stall Catchers help fight Alzheimer's?

Get all the answers in this new great video made by Lindsay & Lisa from out team! You can watch it with Chinese, French, Portugese, Spanish subtitles!

Why aren't we using machines instead of humans to catch stalls?

Stall Catchers Featured

Why aren't we using machines instead of humans to catch stalls?

Updated, 26 Dec 2018: This issue does not stand still! For most recent updates, see this forum thread [http://forum.eyesonalz.com/t/why-arent-we-using-machines-instead-of-humans-to-catch-stalls/518] . -------------------------------------------------------------------------------- A common, and reasonable question that we are frequently asked is "why are you asking people to annotate blood vessels instead of just

Why is "validation" important in Stall Catchers?

Why is "validation" important? Stalls are very rare in Alzheimer's brain, but each is extremely important. Stalls - clogged blood vessels - reduce blood flow to many downstream vessels in the brain, sometimes costing up to 30% of total blood flow. That way, stalls could influence